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Talkin' Pets News

November 26, 2022

Host - Jon Patch

Co-Host - Dr. Suzanne Topor - Livingston Animal & Avian Hospital, Lutz, FL

Producer - Lexi Adams

Network Producer - Ben Boquist

Social Media - Bob Page

Special Guest - Joe Landolina - Creator of Vetigel - helps animals recover quickly and avoid complications like infections and anemia - he joins Talkin' Pets at 530pm ET on 11/26/22

The U.S. Food and Drug Administration conditionally approved Panoquell-CA1 (fuzapladib sodium for injection) for the management of clinical signs associated with acute onset of pancreatitis in dogs. Panoquell-CA1 is an injectable drug intended for use while the dog is hospitalized for treatment of the disease.

Pancreatitis is a painful inflammatory disease of the pancreas that can be life-threatening and generally requires that dogs be hospitalized for treatment. In most cases, it occurs spontaneously. Common factors that increase the chance of developing pancreatitis include when dogs eat something outside of their normal diet (particularly fatty foods), treatment with certain medications, and diseases like diabetes mellitus. It is more common in certain breeds of dogs and in some dogs may become a recurring or chronic condition.

“This is the first drug to address a serious and life-threatening disease that previously could only be managed through supportive care, such as intravenous fluids, pain medication, anti-emetics, and dietary rest,” said Steven M. Solomon, D.V.M., M.P.H., director of the FDA’s Center for Veterinary Medicine. “The conditional approval pathway allows medications like Panoquell-CA1 to reach the marketplace more quickly, and in this case gives dogs suffering from acute onset of pancreatitis earlier access to a drug to manage this disease.”

Conditional approval also means that, when used according to the label, the drug is safe and has a reasonable expectation of effectiveness. Veterinarian access to critical animal drugs provides more options for treating animals with uncommon conditions, serious or life-threatening diseases, or diseases without existing or adequate therapies. The initial conditional approval is valid for one year with the potential for four annual renewals. During this time, the animal drug sponsor must demonstrate active progress toward proving substantial evidence of effectiveness for full approval. If the sponsor does not meet the requirements for substantial evidence of effectiveness at the conclusion of five years, the product can no longer be marketed.

Fuzapladib sodium, the active ingredient in Panoquell, has been approved since 2018 in Japan to improve clinical signs in the acute phase of pancreatitis in dogs, but not in the United States until today. The FDA reviewed data associated with fuzapladib’s use in Japan as part of its assessment of the application for conditional approval.

Veterinarians should advise owners about the possible side effects, which include loss of appetite, digestive tract disorders, respiratory tract disorders, liver disease and jaundice, before using the drug. The FDA encourages dog owners to work with their veterinarian to report any adverse events or side effects potentially related to the use of any drug, including Panoquell-CA1.

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In case you missed it, National Turkey Federation (NTF) Chairman Ronnie Parker presented the National Thanksgiving Turkey named "Chocolate" to President Joseph R. Biden, Jr. during the National Thanksgiving Turkey Presentation. "Chocolate" and his alternate, "Chip," received a formal pardon from the holiday table and will now reside at the Talley Turkey Education Unit at North Carolina State University in Raleigh, North Carolina. This year's presentation marked an exciting milestone as NTF celebrated 75 years of this time-honored American tradition dating back to 1947.

"When I started my career in the turkey industry 44 years ago, I never dreamed that I would have the opportunity to present the National Thanksgiving Turkey at the White House," said NTF Chairman Ronnie Parker. "I want to thank President Biden for welcoming the National Turkey Federation and my family to the White House. Chocolate and Chip had a pretty remarkable day for two turkeys from North Carolina! While this event is a fun tradition that has spanned 75 years, it is also an important reminder of the importance of American turkey producers and agriculture in delivering food to the table. It's an honor to represent these hardworking men and women"

The 2022 National Thanksgiving Turkey and alternate were raised in Monroe, North Carolina, by NTF Chairman Ronnie Parker. Parker is a 44-year veteran of the turkey industry and serves as General Manager of Circle S Ranch. Parker was joined in presenting the National Thanksgiving Turkey by Lexie Starnes, a 4th generation member of the Starnes family involved in the operation of Circle S Ranch. While in Washington, D.C., Chocolate and Chip stayed at the historic Willard InterContinental. Following their visit to the White House, the turkeys will retire to NC State University where they will be under the experienced care of veterinarians, faculty and students within the Prestage Department of Poultry Science.

NTF's participation in the National Thanksgiving Turkey Presentation began in 1947 with President Harry Truman. It has continued for 75 years across 14 successive administrations.

The National Turkey Federation is the national advocate for America's turkey farmers and producers, raising awareness for its members' products while strengthening their ability to profitably and safely deliver wholesome, high-quality and nutritious food to consumers worldwide. More information is available at EatTurkey.org.

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Shy Wolf Sanctuary Education & Experience Center worked with two regional organizations to place more than a dozen animals from Red Gate Farm Rescue. The rescue operation was organized to find new homes for more than a dozen resident animals of Red Gate Farm Rescue after it was forced to terminate its operations due to the declining health of its founder.

 Big Dog Ranch Rescue offered its assistance to transfer eight domesticated dogs to its newly opened expansion facility in Shorter (AL). Their on-site veterinarian is conducting full health evaluations of the animals prior to placing them up for adoption. Interested adopters who would like to provide a new permanent home and family to these precious dogs, or another in need, are required to provide an approved adoption application and appointment with Big Dog Ranch Rescue. For more information, visit www.bdrr.org/meet-our-dogs.

 Additionally, Shy Wolf Sanctuary coordinated with Alyssa’s Animal Sanctuary in the placement of two horses from Red Gate Farm Rescue. Alyssa’s Animal Sanctuary recently relocated from Southwest Florida to Valdosta (GA) to expand its operations.

 “This rescue mission would not have been possible without the support and coordination of agencies throughout the region working from the heart and for the animals,” said Deanna Deppen, Executive Director of Shy Wolf Sanctuary Education & Experience Center.

 Shy Wolf Sanctuary is beyond grateful for the support and assistance to this rescue operation. The team is continuously working and coordinating with other rescue organizations to help relocate the needy animals with the hopes of finding them a new loving home and family.

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On the evening of November 15, two men mutilated a friendly cat named Scruffy. The heinous crime was captured on video and now the Pomona California Police are hopeful that someone will come forward with information about the sickening act in order to help them make arrests.

A surveillance video provides critical details about this animal cruelty case. A white car can be seen parking in front of a business at 560 Union Avenue around 9:30 p.m.

Then, the cat is shot and can be seen flailing in the parking lot.

The men proceed to jump over the fence and walk up to the cat; one man removes a “sharp object” believed to be a knife. The man slices open Scruffy’s body with the object while the other man records the appalling act with his cell phone.

Scruffy’s mutilated body was found the next morning and the Pomona Police, and Inland Valley Humane Society were notified. Employees at CFR Patio have said that Scruffy was one of several homeless cats that they help care for.

Scruffy was just about to be adopted…but her happily-ever-after was cruelly stolen before she was able to enjoy it. Those who knew her are disgusted that her life was cut short in such a brutal manner, and they hope that the men responsible for her death will be found and held accountable.

Animal Victory wants these psychopaths to be found, arrested, and charged! We are hoping to raise funds to help provide a $500 reward for information leading to the identification, arrest, and conviction of the men responsible for this disgusting act.

According to the U.S. Department of Justice, “FBI research indicates that most serial killers, school shooters, and mass murderers tortured animals as children. Another form of abuse, dogfighting, is also tied to criminal behavior beyond the harm to the animals.”

Please add your name to the petition today and share this petition with the hope that it will bring forward the information needed to arrest these monsters before they kill again. Visit www.animalvictory.org

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One of the world's biggest goldfish has been caught, weighing in at 67 lbs. 4 oz.!

The enormous specimen was found in a fishery in France by British angler Andy Hackett, who reportedly spent over 25 minutes reeling the fish in, according to Daily Mail.

Nicknamed "The Carrot," the fish is a hybrid species of a leather carp and koi carp, which are traditionally orange in color.

The Carrot is thought to be more than 20 years old, as it was placed in the BlueWater Lakes fishery in Champagne, France, by Jason Cowler when it was a guppy.

"We put The Carrot in about 20 years ago as something different for the customers to fish for. Since then it has grown and grown but it doesn't often come out," Cowler said. "She is very elusive."

"I always knew The Carrot was in there but never thought I would catch it," Hackett said of his find.

The Carrot is 30 lbs. heavier than what was previously considered to be the world's biggest goldfish, caught by Jason Fugate in Minnesota in 2019. It is also more than twice the size of a 30 lb. koi carp caught by Raphael Biagini in the south of France in 2019.

"I knew it was a big fish when it took my bait and went off side to side and up and down with it. Then it came to the surface 30 or 40 yards out and I saw that it was orange," continued Hackett. "It was brilliant to catch it but it was also sheer luck."

Hackett released The Carrot back into the lake after posing for photos with the creature.

"She is in excellent health and condition," Cowler noted. "Congratulations to Andy on a great catch."

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At the 19th meeting of the Conference of the Parties to CITES, the Parties agreed to reduce by 610 the number of leopard hunting trophies and skins for personal use that can be exported from certain African countries to other countries. Currently, CITES allows the export from twelve African countries of up to 2,648 leopard trophies and skins for personal use. Kenya and Malawi asked to remove their names from the list of countries that can export these items while Ethiopia asked to reduce its export quota from 500 to 20 per year.

The decisions are preliminary and need to be confirmed later this week.

After the vote, Sarah Veatch, director of wildlife policy at Humane Society International, released the following statement:

“The leopard is a threatened species with a declining wild population in Africa where trophy hunting—a bloodsport with severe consequences for animal welfare and conservation efforts—jeopardizes their survival. Current export quotas are not based on science; and we therefore welcome the Parties’ decision to support the removal of export quotas for Kenya and Malawi and to significantly reduce Ethiopia’s quota for leopards. We urge the Parties to follow Kenya and Malawi’s example and take additional measures to bring leopard export quotas for other countries down to zero as well.”

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An initiative aimed at eliminating discriminatory practices against transgender, non-binary, and gender non-conforming individuals in the veterinary profession has received support from two industry associations.

The American Veterinary Medical Association (AVMA) and the Veterinary Medical Association Executives (VMAE) have signed Pride Veterinary Medical Community’s (PrideVMC’s) Gender Identity Bill of Rights (GIBOR).

Coauthored by Erika Lin-Hendel, VMD, PhD; Ewan Wolff, PhD, DVM, DACVIM; and Jenna Ward, DVM, the document serves as a minimum foundation to identify and eliminate discriminatory practices in the industry. It calls for several rights to be implemented within the profession, including the right to identity, names, pronouns, and privacy; freedom of gender expression; and protection from coworker and client discrimination/harassment.

AVMA and VMAE’s signing of the GIBOR marks “a step forward” in enhancing diversity, equity, and inclusion (DEI) in the veterinary profession, PrideVMC says.

“We are thrilled with the announcement that both AVMA and VMAE have joined the numerous other organizations as signatories in support of these basic human rights for transgender, non-binary, and gender non-conforming individuals,” says the group’s president, Abby McElroy, DVM, MS. “[Their] support represents a higher order of partnership within organized veterinary medicine that we hope, along with other major groups, can lead to safe inclusive space within the entire profession, including our AVMA-accredited teaching institutions.”

As of early November, the GIBOR counts among its signatories 856 individuals and 177 organizations, including national and international associations, colleges and schools of veterinary medicine, veterinary practices, and animal health companies across the industry.

“Supporting the Gender Identity Bill of Rights is consistent with our belief in inclusion and will help to advance the AVMA’s diversity initiatives,” says AVMA president, Lori Teller, DVM, DABVP (canine/feline), CVJ. “The GIBOR will help some people who may not have felt welcomed in the past to feel more comfortable and supported in our great profession in the future. We thank PrideVMC for its advocacy, which will help all members of the veterinary community feel included and respected.”

“VMAE serves executives who manage state, regional, and specialty veterinary medical associations,” adds VMAE president, Tim Atkinson. “We actively promote diversity within our community through our programs and we are proud to sign on to the GIBOR. It provides us with a set of guiding principles to follow so we can ensure our association is welcoming to all, regardless of their gender identification.”

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Dogs hospitalized with pancreatitis can now benefit from newly approved treatment.

Panoquell-CA1 has been granted conditional approval from the U.S. Food and Drug Administration (FDA) for the management of clinical signs associated with acute onset of pancreatitis in canines. The product, which contains the active ingredient fuzapladib sodium, is an injectable drug intended for use while a dog is hospitalized.

Pancreatitis is a painful inflammatory disease of the pancreas, which can be life-threatening and generally requires dogs be hospitalized for treatment, FDA reports. While it mostly occurs spontaneously, common factors that increase the chance of dogs developing pancreatitis include consuming foods outside of their normal diet (particularly fatty foods), receiving treatment with certain medications, and diseases, like diabetes mellitus.

Pancreatitis is more common in certain breeds of dogs and, in some cases, may become a recurring or chronic condition.

“This is the first drug to address a serious and life-threatening disease that previously could only be managed through supportive care, such as intravenous fluids, pain medication, anti-emetics, and dietary rest,” says Steven M. Solomon, DVM, MPH, director of FDA’s Center for Veterinary Medicine.

Panoquell-CA1’s initial conditional approval is valid for one year with the potential for four annual renewals, FDA says. During this time, the drug’s sponsor, Ishihara Sangyo Kaisha, must demonstrate active progress toward proving substantial evidence of effectiveness for full approval. If these requirements are not met at the conclusion of five years, the product can no longer be marketed, FDA reports.

Fuzapladib sodium, the active ingredient in Panoquell-CA1, has been approved in Japan to improve clinical signs in the acute phase of pancreatitis in dogs since 2018. FDA reviewed data associated with fuzapladib’s use in Japan as part of its assessment of the application for conditional approval.

“The conditional approval pathway allows medications like Panoquell-CA1 to reach the marketplace more quickly, and in this case gives dogs suffering from acute onset of pancreatitis earlier access to a drug to manage this disease,” Dr. Solomon says.

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Morris Animal Foundation (MAF) will fund 2 separate studies conducted by University of Georgia and Tufts University both focused on using nonsurgical methods to control reproductive capacity in cats. This is in response to the issue of an estimated 60 million to 100 million free-roaming, community cats in the United States. MAF is looking for new strategies that move beyond trap/neuter/release programs.

MAF was first looking for research proposals on this issue back in April 2022.

“The importance of finding viable, safe, humane and cost-effective techniques for nonsurgical sterilization in community cats cannot be overstated,” said Kathy Tietje, MBA, PhD, vice president of scientific operations at Morris Animal Foundation, in an organizational release.1 “We’re excited about these innovative projects and their impact on population control of this specific group of cats.”

In line with its mission, MAF aims to bridge the gap between science and resources in order to advance the health of animals. By finding new ways for cat sterilization, MAF wants to reduce the number of cats entering the shelter system and improve overall feline health outcomes. According to MAF, an additional benefit would be reducing the environmental impact of free-roaming, community cats through humane population control.

Both projects are slated to begin in 2023 and are expected to last 12-24 months. The project at the University of Georgia is aimed at developing an oral vaccine to decrease male cat fertility by reducing reproductive hormone levels. The Tufts University project focuses on decreasing hormone levels in female cats through an injectable medication.1

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Minimizing fear, anxiety, and stress in cats and, by extension, increasing feline visits is the goal of two newly revised industry resources.

The International Society of Feline Medicine (ISFM) and the American Association of Feline Practitioners (AAFP) have jointly published two guidelines detailing how veterinarians can best implement positive, respectful interactions with feline patients and reduce stress associated with the veterinary environment.

Endorsed by more than 25 international veterinary and feline welfare organizations, the 2022 AAFP/ISFM Cat Friendly Veterinary Interaction Guidelines: Approach and Handling Techniques and the 2022 ISFM/AAFP Cat Friendly Veterinary Environment Guidelines cover all aspects of a cat’s veterinary experience, including the journey to the practice, as well as interactions with veterinary team members and the clinical environment.

The guides include practical tips related to several key areas, including:

  • Implementing cat-friendly interactions and minimal handling, allowing a feline patient to have a sense of control and choice.
  • Educating cat caregivers about how to reduce distress when traveling to the veterinary practice (including carrier training).
  • Creating an experience that considers the animal’s natural behaviors and altering an approach to each individual cat.
  • Creating an environment that considers and implements ways to reduce fear/anxiety and promotes emotions and behaviors cats find comforting.
  • Ensuring the entire veterinary team understands species-specific behavior and individual differences, as well as how this affects the entire veterinary visit/experience.
  • Understanding how to identify the cat’s emotional state and the subsequent behavioral response (and what to do in each situation).

“We are extremely proud of our new guidelines,” says ISFM head, Nathalie Dowgray, BVSc, MRCVS, MANZCVS (feline), PG Dip IAWEL. “They have been a lot of hard work, with large amounts of literature to review and multiple time zones to work across, but the effort has been worth it. We hope all veterinarians working with cats will take the time to read them and apply the concepts and ideas to their clinics and to how they personally interact with their feline patients.”

“We’re excited to launch these guidelines to the veterinary community,” adds AAFP CEO, Heather O’Steen, CAE. “They will enhance feline welfare, caregiver loyalty, and human safety, as well as create more positive veterinary visits for all! They will become the foundation for feline care and the veterinary experience.”

The two sets of guidelines have been published in a cat-friendly special issue of the Journal of Feline Medicine and Surgery (JFMS), along with a suite of supplemental resources.

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Asymmetry of movement remains a telltale sign of lameness, likely due to discomfort or pain. Have you ever stopped to wonder how much pain a lame horse experiences while standing casually in its stall or paddock? A Swedish research team recently asked this question. The team compared four different pain scales using eight healthy horses with experimentally induced, temporary orthopedic pain.*

Lameness examinations and pain assessments were performed prior to the joint injection, during the short-term inflammatory period, and several times during and after resolution of joint inflammation. Four different pain scales were used in this study: Horse Grimace Scale, Equine Utrecht University Scale of Facial Assessment of Pain, Equine Pain Scale, and Composite Orthopedic Pain Scale (COPS).

“These scales use various assessments of facial expressions, behaviors, and physiology variables to create a ‘pain score’ for the horse,” explained Kathleen Crandell, Ph.D., a Kentucky Equine Research nutritionist. Lameness was assessed objectively by placing spherical markers on the horse and infrared motion capture cameras. Experienced equine practitioners also subjectively evaluated each horse.

“The study showed that COPS was the most reliable scale, indicating significant associations between total pain score and total movement asymmetry score. This scale used more than just facial expressions to assess pain, as facial expressions may be more challenging to interpret for some observers than body postures or behaviors,” Crandell said.

Researchers found some pain scores to be 0 after induction of joint inflammation. “The researchers suggested that these horses may not have continuously experienced pain at rest or they were able to adjust their weight, limiting the load on the painful limb. As a result, their pain score decreased. The researchers also cited a study in which horses hid their discomfort when evaluators were present,” Crandell explained.

The researchers also noted that these scales may not be valid for different types of pain or even different types of orthopedic pain. In other words, the amount of pain a horse experiences at rest after surgery may not be the same as what a laminitic pony experiences.

“The study results suggest that a pain assessment tool applied in resting horses used in conjunction with lameness examination grading may help decide the pain level of orthopedic patients. Having this information ensures horses receive appropriate pain control,” said Crandell. In addition to anti-inflammatory medications, a staple in managing orthopedic patients, experts recommend adding oral joint health supplements to help support joint health for those horses.

“For joint comfort, supplementing with hyaluronic acid (HA) may help lubricate joints. Synovate HA helps maintain cartilage health and elasticity, joint fluid viscoelasticity, and lubrication of the entire joint mechanism. Further, HA has anti-inflammatory properties, which are useful for high-motion joints,” summarized Crandell.

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Pregnant mares, like some women, have changes in feed preferences and feeding behaviors that may benefit their growing fetuses. Those same “cravings,” however, may also be potentially harmful to their own health. These were the key findings recently reported by researchers from Southern Illinois University.* In this novel study, five pregnant mares in the last 120 days of gestation and four open mares were offered small amounts (0.5 lb or 0.23 kg) of a concentrate with one of three oil-based palatants. A palatant is any ingredient used to make a feed, supplement, or treat taste better. Based on previous studies on preferred flavors, apple and anise palatants were tested, and corn oil served as a control. The three portions were placed in separate pans beside one another in an empty test stall for three consecutive days for a total of five observation periods. Horses had access to all three feed pans for 20 minutes. Each session was video recorded, and various behaviors were documented. These included smelling and hovering over the portions as well as ingesting and chewing behaviors. Time taken to smell and finish each diet were also recorded. Gestating mares demonstrated significantly more olfactory behaviors compared to open mares. Further, their consumption rate was significantly faster, particularly for the apple-flavored feed. The pregnant mares also exhibited fewer stress-related behaviors during the testing periods, such as pawing, pacing, and elimination.

“The researchers suggested that the increase in olfactory investigation of the feeds prior to consumption could be an evolutionary mechanism designed to encourage more careful examination of feedstuffs prior to consumption,” explained Katie Young, Ph.D., a nutritionist for Kentucky Equine Research. She added, “This increased investigation of a feed prior to ingestion could help mares avoid consuming feeds that are potentially toxic or harmful to the developing fetus.” On the flip side, pregnant mares consumed the feeds relatively rapidly, which may negatively affect their own health over time. “During the last months of pregnancy, a mare may require 30% more daily calories than a mare at maintenance or in early pregnancy. This higher caloric demand may help explain the increase in rate of feed intake in the pregnant mares observed in this study,” she said. Any horse that consumes feed quickly, however, is at risk of choke or even colic. “Bolting feed increases the risk of choke as inadequate chewing may allow large feed particles to block the esophagus. Chewing also stimulates saliva production in horses, which helps moisten and move feed particles through the esophagus. Thus, decreased chewing may result in insufficient saliva production, also contributing to choke.”

According to the study, the changes in feeding behavior and olfaction could be related to hormone levels. In other species, the decreased estrogen and increased progesterone production that occurs in the latter stages of pregnancy may bump up feed intake. In addition to ensuring mares receive diets with sufficient calories to meet their higher energy needs, their diets must be balanced to supply essential nutrients, such as amino acids, vitamins, and minerals, to support their own requirements as well as those of the growing fetus. “A concentrate feed formulated for broodmares that contains high-quality protein sources and appropriate vitamin and mineral supplementation along with good-quality forage is usually a good ration for pregnant mares,” Young recommended. “In some situations, an easy-keeping pregnant mare with access to high-quality pasture or hay may meet her calorie needs without additional feed or with lower than minimum recommended amounts of a fortified feed for pregnancy. In such cases, a balancer pellet will provide essential nutrients without adding additional calories that may result in excessive weight gain.”   +++++++++++++++++++++++++++++

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